European stocks dropped in early trading on Friday after more Fed policymakers signalled they will start to raise U.S. interest rates in March to combat inflation.
Asian shares fell after Fed Governor Lael Brainard became the latest and most senior U.S. central banker to indicate that the U.S. Federal Reserve will hike rates in March.
Other Fed officials have also shown their willingness to raise rates, after data this week showed U.S. consumer prices surged 7% year-on-year.
At 0835 GMT the MSCI world equity index, which tracks shares in 50 countries, was down 0.2%, having fallen overall so far in January.
The STOXX 600 was down 0.5%, and on track for its worst week since November last year.
"It’s clearly the impact of monetary policy tightening that’s being felt in markets here," said Guillaume Paillat, multi-asset portfolio manager at Aviva Investors.
"Why would I buy expensive low-profit growth stocks when the central bank is starting to tighten monetary policy?"
Paillat, who is expecting at least four Fed rate hikes this year, said it was "pretty much a done deal" that the hiking cycle would start in March.
"What matters over the coming days is going to be more about earnings," he added. "There’s still a bit of room for earnings to surprise to the upside."
The dollar fell for a fourth consecutive day, hitting a two-month low as investors took profit on long-dollar bets. At 0849 GMT the dollar index was at 94.667 and was on track for a 1.1% weekly drop - its biggest since May last year.
The euro was up around 0.2% at $1.14725.
U.S. Treasury yields were steady, with the 10-year yield around 1.73% - below the two-year highs hit on Monday .
European government bond yields were up by around one basis point, having generally moved lower this week as investors sought safer assets.
The European bond market has been calm in the face of a possible government shake-up in Italy and ahead of French elections in April.
Meanwhile the five-year Japanese government bond yield jumped to its highest since January 2016 and the yen rose after a Reuters report that Bank of Japan policymakers are debating how soon they can start an eventual interest rate hike.
Such a move could come even before inflation hits the bank's 2% target, sources said.
The dollar was down around 0.4% against the yen, at 113.750 .
The British pound was up 0.2% against the dollar, at $1.37315.
UK GDP data showed that Britain's economy grew faster than expected in November and had finally surpassed the size it was before the country went into its first COVID-19 lockdown.
Oil futures were a touch higher, reversing recent losses, helped by the weaker U.S. dollar.
Bitcoin was little changed, around $42,565, having recovered somewhat since it slipped below $40,000 earlier this week . The cryptocurrency has lost around 38% of its value since it hit an all-time high of $69,000 in March.